Under My Umbrella – The dirty dozen of nutritional supplements

by Ma. Teresa L. Ungson
Do you still remember an earlier feature in this column on the Dirty Dozen of Cosmetics?  Well, guess what?  A dozen ingredients commonly found in dietary supplements should be avoided, according to a new report, because they are linked to cancer, coma, kidney and liver damage, heart problems, and death.
Compiled by Consumer Reports in the US, the report singles out 12 dietary supplement ingredients termed the ‘’dirty dozen.” “The dozen we call out in this report are by no means the only dangerous ingredients,” says Nancy Metcalf, senior program editor at Consumer Reports.  “They are the ones we chose to highlight.”
Researchers from Consumer Reports worked with experts from the Natural Medicines Comprehensive Database, an independent research group, first identifying from a database of nearly 1,100 ingredients a group of about 25 ingredients that had been linked to serious problems either by research studies or case reports.
Next, they whittled down the list to the 12, evaluating adverse events as well as how available the ingredients were and how aggressively the products containing them are promoted, Metcalf says. ‘’It’s to a certain extent a subjective thing,” she says of the process. She and her colleagues combed medical literature and other data to arrive at the list of 12 that Consumer Reports advises people to avoid.
On the list are these ingredients, their uses, and what evidence Consumer Reports has they may lead to problems:
1. Aconite, used for joint pain, wounds, gout, and inflammation, but linked with nausea, vomiting, heart rhythm disorders, respiratory system paralysis, and death.
2. Bitter orange, used for weight loss, allergies, and nasal congestion, but linked with fainting, heart rhythm disorder, heart attack, stroke, and death.
3. Chaparral, used for weight loss, colds, infections, inflammation, cancer, and detoxification, but linked to kidney and liver problems.
4. Colloidal silver, used for fungal and other infections, Lyme disease, rosacea, psoriasis, food poisoning, chronic fatigue syndrome, and HIV/AIDS, but linked to bluish skin color, mucous membrane discoloration, neurological problems, and kidney damage.
5. Coltsfoot, used for cough, sore throat, laryngitis, bronchitis, and asthma, but linked to cancer and liver damage.
6. Comfrey, used for cough, heavy menstrual periods, chest pain, and cancer, but linked to liver damage and cancer.
7. Country mallow, used for allergies, asthma, weight loss, bronchitis, and nasal congestion, but linked to heart attack and arrhythmia, stroke, and death.
8. Germanium, used for pain, infections, glaucoma, liver problems, arthritis, osteoporosis, heart disease, HIV/AIDS, and cancer, but linked to kidney damage and death.
9. Greater celandine, used for upset stomach, irritable bowel syndrome, liver disorders, detoxification, and cancer, but linked to liver damage.
10. Kava, used for anxiety (and is possibly effective, according to Consumer Reports), but linked to liver damage.
11. Lobelia, used for coughs, bronchitis, asthma, smoking cessation, but linked to toxicity, with overdose linked with fast heartbeat, very low blood pressure, coma, and possible death.
12. Yohimbe, used as an aphrodisiac, for chest pain or diabetic complications, depression, and erectile dysfunction (and possibly effective, according to Consumer Reports), but linked to high blood pressure and rapid heart rate at usual doses and at high doses linked to severe low blood pressure, heart problems, and death.
The possible problems listed for each are based on either case reports or clinical research, according to Metcalf. The report updates a previous investigation on supplements done by Consumer Reports.
Despite the popularity of supplements, Metcalf says, “You need to be extremely careful about buying nutritional supplements, because there are several different ways they can be harmful.”
Some supplements, she says, include ingredients that can be ‘’inherently harmful” and lack proof of effectiveness.
In other cases, manufacturer error may lead to excess amounts of ingredients in products. That was the case for a Tennessee man who took a supplement and experienced diarrhea, joint pain, hair loss, lung problems, and had fingernails and toenails fall off. In his case, detailed in the report, an inspection of the supplement maker’s facilities found the samples had more than 200 times the labeled amount of selenium and up to 17 times the recommended intake of chromium, according to the report, citing FDA information.
However, the report is termed ‘’a little bit sensationalized” by Andrew Shao, PhD, a spokesman for the Council for Responsible Nutrition, a trade group.  “Any time you pick adverse experiences from a handful of individuals, you know it is being sensationalized,” he says. “It doesn’t represent the totality of the evidence.” “Some of these ingredients [in the report] have been flagged by the FDA years ago,” Shao says. But he also acknowledges that despite this, the ingredients are still readily available.  Like Consumer Reports, he says more enforcement power is needed by the FDA.
Another expert took exception to some parts of the report, saying some of the ingredients Consumer Reports calls dangerous are not when used appropriately. But he agrees with other points. “I agree some should be avoided,” says Mark Blumenthal, founder and executive director of the American Botanical Council, a nonprofit research and education organization in Austin, Texas. On his list: coltsfoot, comfrey, and yohimbe.
Consumers should always discuss supplement use with their health care provider, Blumenthal says. His organization favors stronger regulations, including the requirement to report adverse events, he says.
In the report, Consumer Reports also identifies 11 supplements “to consider.” On that list: calcium, cranberry, fish oil, glucosamine sulfate, lactase, lactobacillus, psyllium, pygeum, SAMe, St. John’s wort, and vitamin D.
For safer supplement use, Metcalf says, consumers can beware of products that have been linked with the most problems — those for weight loss, sexual enhancement, and body building.
A product that has a “USP Verified” mark means the manufacturer has asked the U.S. Pharmacopeia, a nonprofit standards-setting authority, to verify the quality, purity, and potency of its raw ingredients or the finished product.
Consumers can also check out alerts and advisories regarding dietary supplements on the web sites of the National Institutes of Health Office of Dietary Supplements and the FDA.
As consumers, we should equip ourselves with the latest information to best protect our health.  Nutritional supplements are not really “required” unless a person is deficient in a certain vitamin or mineral.  Most of these supplements in the Philippines are not allowed to have therapeutic claims since most don’t have enough studies to substantiate therapeutic claims.
On a nutritionist viewpoint, as long as one is eating a balanced diet and living a healthy lifestyle, nutrtitional supplements are not necessary.  Most of the available supplements provide more than a 100% of our Required Energy and Nutrient Intake (RENI).  Taking more than what is required by our body can lead to toxicity especially if these are not water soluble nutrients (or easily flushed out by our body).
It would be best to always consult a health practitioner (doctor or nutritionist-dietitian) before taking certain nutritional supplements specially those cited earlier.  Let us not take risks with our health.  With all the technology around us, it would be best that we do our own research and consult our doctor if we really need a certain supplement.  Otherwise, let’s save our money for other important needs.
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